Commanders tend to be important pieces to decks, and are often required to be on the field.
Leadership Vacuum is an Instant of 2U that puts all commanders target player controls into the commander zone. This means that it gets around Shroud and Hexproof as it targets the player and not the commander. As well evading other keywords such as Indestructible, Ward, Regeneration or Persist.
In addition it does not destroy the commander but puts it into the command zone this means it gets around death triggers and denies your opponent the choice of where to put their commander. If your opponent is playing partner commanders it will return both of them to the command zone, and it draws you a card.